Was One Wrong?


In laurels of 's 10th anniversary, I'd similar to denote a novel occasional feature:

Was I Wrong?


In science, equally inwards life, nosotros larn from our mistakes. We can't deed forrad if nosotros don't acknowledge nosotros were incorrect too revise our entrenched theory (or tentative hypothesis) when faced amongst contradictory evidence. Likewise, it's possible that unopen to of the critiques inwards this weblog are no longer valid because additional bear witness shows that the authors were correct. And vindicated. At to the lowest degree for now...

I've been collecting possible instances of this phenomenon for months, too I'll preview 2 of these today.

(1) In Nov 2015, I said that Obesity Is Not Like Being "Addicted to Food". Drugs of abuse are consistently associated amongst Karlsson et al., 2015). Conversely, μ-opioid receptor (MOR) binding is reduced, which supports lowered hedonic processing. After the women had bariatric surgery, MOR returned to command values, piece the unaltered D2 receptors stayed the same.

However, a recent written report inwards mice “points to a causal link betwixt striatal dopamine signaling too the outcomes of bariatric interventions” (Han et al., 2016). How relevant is this novel finding for clinical studies inwards humans?


(2) In unopen to other post, I poo-pooed the notion that in that place is One Brain Network for All Mental Illness. However, a subsequent newspaper inwards Molecular Psychiatry claimed that mutual psychiatric disorders portion the same genetic beginning (Pettersson et al., 2015). If so, could this final result inwards mutual encephalon abnormalities alterations across disorders?


In the future, I'll guide maintain a closer hold off at these too other examples to run across if I should revise my opinions.
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Was One Wrong?
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